Archive for April, 2009

Apr 10 2009

Omega-3 protect prostates from cancer

Increased intake of omega-3 fatty acids protect against advanced prostate cancer, according to new research from the University of California San Francisco.
According to findings published in the journal Clinical Cancer Research, omega-3 essential fatty acids may reduce prostate cancer risk by modifying a specific variant of the COX-2 gene, a known contributor to chronic inflammation.
The variant known as rs4647310 is linked to a five-fold increased risk of advanced prostate cancer, report the researchers, but high intakes of omega-3 may reduce the risk, even if people carry the COX-2 variant.
The highest average intakes of omega-3 fatty acids were associated with a 63 percent reduction in the risk of aggressive prostate cancer, compared to men with the lowest amount of long chain omega-3 fatty acids, said the researchers.
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The study adds to a growing body of evidence linking omega-3 to potential cancer benefits. Results in the journal Cancer Epidemiology, Biomarkers & Prevention reported that higher intake of the omega-3 fatty acids DHA (docosahexaenoic acid) and EPA (eicosapentaenoic acid) may cut the risk of developing prostate cancer by 40 per cent. Interestingly, the new study reports no relationship between fish intake and the risk of prostate cancer.
Over half a million new cases of prostate cancer are diagnosed every year worldwide, and the cancer is the direct cause of over 200,000 deaths. More worryingly, the incidence of the disease is increasing with a rise of 1.7 per cent over 15 years.

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