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Jun 03 2008

Nettle Root

Published by at 1:46 pm under Vitamins & Supplements

The roots of the stinging nettle are useful for male hormone balance. Extracts known as lignans derived from the roots have the ability to bind sex hormone binding globulin (SHBG). When SHBG is bound, this may allow for more unbound, or free (bioavailable) testosterone to be available for biological processes and this may prevent SHBG from binding to the prostate gland, which may prevent prostatic enlargement via SHBG binding 5. Bioavailable testosterone represents the fraction of circulating testosterone that readily enters cells and better reflects the bioactivity of testosterone. The better bioactivity means a more healthful benefit from testosterone.1 Stinging nettle root constituents also act to control the growth of prostatic cells and resultant symptoms.2-3 Nettle root also contains another constituent known as beta-sitosterol which has positive effects on testosterone levels and prostate health.4

Griffin Medical Group recommends 250mg twice a day between meals which may allow more free testosterone.

Yours in health,

Griffin Medical Group


1. Hyrb D et al. The effect of extracts of the roots of the stinging nettle (Urtica dioca) on the interaction of SHBG with its receptor on human prostatic membranes. Planta Med, 1995, 61:31-32.
2. Konrad L, Muller HH, Lenz C, et al. Antiproliferative effect on human prostate cancer cells by a stinging nettle root (Urtica dioica) extract. Planta Med 2000;66:44-7.
3. Lichius JJ, Muth C. The inhibiting effects of Urtica dioica root extracts on experimentally induced prostatic hyperplasia in the mouse. Planta Med 1997;63:307-10.
4. Durak I, Biri H, Devrim E, et al. Aqueous extract of Urtica dioica makes significant inhibition on adenosine deaminase activity in prostate tissue from patients with prostate cancer. Cancer Biol Ther 2004;3:855-7.
5. Schottner M, Gansser D, Spiteller G, et al. Lignans from the roots of Urtica dioica and their metabolites bind to human sex hormone binding globulin (SHBG). Planta Med 1997;63:529-32.

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